Oct 14 2024
Kadidia Samassekou, Elisabeth E. Garland-Kuntz, Vaani Ohri, Isaac J. Fisher, Satchal K. Erramilli,Kaushik Muralidharan, Livia M. Bogdan, Abigail M. Gick, Anthony A. Kossiakoff, Angeline M. Lyon
bioRxiv 2024 September 12
PMID: 39314324 PMCID: PMC11418990 DOI: 10.1101/2024.09.11.612521
Phospholipase Cε (PLCε) increases intracellular Ca 2+ and protein kinase C (PKC) …
Oct 14 2024
Ireneusz Górniak, Zachery Stephens, Satchal K. Erramilli, Tomasz Gawda, Anthony A. Kossiakoff & Jochen Zimmer
Nature Structural & Molecular Biology (2024)
PMID: 39322765 DOI: 10.1038/s41594-024-01389-1
Hyaluronan (HA) is an essential component of the vertebrate extracellular matrix. It is a heteropolysaccharide of N-acetylglucosamine (GlcNAc) and glucuronic acid (GlcA) reaching …
Oct 14 2024
Yaqi Liu, Chelsea M Brown, Nuno Borges, Rodrigo N Nobre, Satchal Erramilli, Meagan Belcher Dufrisne, Brian Kloss, Sabrina Giacometti, Ana M Esteves, Cristina G Timoteo, Piotr Tokarz, Rosemary Cater, Yasu S Morita, Anthony A Kossiakoff, Helena Santos, Phillip J Stansfeld, Rie Nygaard, Filippo Mancia
bioRxiv 2024 September 18
PMID: 39345506 …
Oct 14 2024
Yaqi Liu, Chelsea M. Brown, Satchal Erramilli, Yi-Chia Su, Po-Sen Tseng, Yu-Jen Wang, Nam Ha Duong, Piotr Tokarz, Brian Kloss, Cheng-Ruei Han, Hung-Yu Chen, José Rodrigues, Margarida Archer, Todd L. Lowary, Anthony A. Kossiakoff, Phillip J. Stansfeld, Rie Nygaard, Filippo Mancia
bioRxiv 2024 September 17
PMID: 39345558 PMCID: PMC11429727 DOI: …
Aug 12 2024
Tomasz Slezak, Kelly M. O’Leary, Jinyang Li, Ahmed Rohaim, Elena K. Davydova, Anthony A. Kossiakoff
bioRxiv 2024 August 08.
PMID: 39211271 PMCID: PMC11361062 DOI: 10.1101/2024.08.06.606809
We have developed a portfolio of antibody-based modules that can be prefabricated as standalone units and snapped together in plug-and-play fashion to create uniquely powerful …
Aug 07 2024
Jane E. Lodwick, Rong Shen, Satchal Erramilli, Yuan Xie, Karolina Roganowicz, Anthony A. Kossiakoff, Minglei Zhao
bioRxiv 2024 Jun 27:2024.06.27.601040. doi: 10.1101/2024.06.27.601040.
PMID: 38979142 PMCID: PMC11230398 DOI: 10.1101/2024.06.27.601040
Vault is a massive ribonucleoprotein complex found across Eukaryota. The major vault protein (MVP) oligomerizes into an ovular cage, which …
Aug 07 2024
Sewwandi S Rathnayake, Satchal K Erramilli, Anthony A Kossiakoff, Alex J Vecchio
Science Direct Structure 8 October 2024
PMID: 39383874 DOI:10.1016/j.str.2024.09.015
Pathogenic strains of Clostridium perfringens secrete an enterotoxin (CpE) that causes prevalent, severe, and sometimes deadly gastrointestinal disorders in humans and domesticated animals. CpE binds selectively …
Aug 07 2024
Satchal K Erramilli, Pawel K Dominik, Chinemerem P Ogbu, Anthony A Kossiakoff, Alex J Vecchio
Commun Biol. 2024 Jun 17;7(1):733. doi: 10.1038/s42003-024-06437-6.
PMID: 38886509 PMCID: PMC11183071 DOI: 10.1038/s42003-024-06437-6
Claudins are a 27-member family of ~25 kDa membrane proteins that integrate into tight junctions to form molecular barriers at …
Jun 20 2024
Tong Lan, Tomasz Slezak, Jinyue Pu, Julia Zinkus-Boltz, Sarbani Adhikari, Joel R. Pekow, Vibha Taneja, Joaquin Zuniga, Itzel A. Gómez-García, Nora Regino-Zamarripa, Mushtaq Ahmed, Shabaana A. Khader, David T. Rubin, Anthony A. Kossiakoff, and Bryan C. Dickinson
ACS Chem. Biol. June 6, 2024 © 2024 American Chemical Society
PMID: 38843544 …
Jun 20 2024
Lin Zhang, Hong-Chao Duan, Marcin Paduch, Jingyan Hu, Chi Zhang, Yajuan Mu, Houwen Lin, Chuan He, Anthony A. Kossiakoff, Guifang Jia, Liang Zhang
Zitierweise: Angew. Chem. Int. Ed. 2024, 63, e202313900
PMID: 38158383 DOI: 10.1002/ange.202313900
N1-methyladenosine (m1A) is a prevalent post-transcriptional RNA modification, and the distribution and dynamics …