Aug 12 2024
Tomasz Slezak, Kelly M. O’Leary, Jinyang Li, Ahmed Rohaim, Elena K. Davydova, Anthony A. Kossiakoff
bioRxiv 2024 August 08.
PMID: 39211271 PMCID: PMC11361062 DOI: 10.1101/2024.08.06.606809
We have developed a portfolio of antibody-based modules that can be prefabricated as standalone units and snapped together in plug-and-play fashion to create uniquely powerful …
Aug 07 2024
Jane E. Lodwick, Rong Shen, Satchal Erramilli, Yuan Xie, Karolina Roganowicz, Anthony A. Kossiakoff, Minglei Zhao
bioRxiv 2024 Jun 27:2024.06.27.601040. doi: 10.1101/2024.06.27.601040.
PMID: 38979142 PMCID: PMC11230398 DOI: 10.1101/2024.06.27.601040
Vault is a massive ribonucleoprotein complex found across Eukaryota. The major vault protein (MVP) oligomerizes into an ovular cage, which …
Aug 07 2024
Sewwandi S Rathnayake, Satchal K Erramilli, Anthony A Kossiakoff, Alex J Vecchio
bioRxiv 2024 Jul 12:2024.07.11.603128. doi: 10.1101/2024.07.11.603128.
PMID: 39026804 PMCID: PMC11257603 DOI: 10.1101/2024.07.11.603128
Pathogenic strains of Clostridium perfringens secrete an enterotoxin (CpE) that causes prevalent, severe, and sometimes deadly gastrointestinal disorders in humans and domesticated animals. CpE …
Aug 07 2024
Satchal K Erramilli, Pawel K Dominik, Chinemerem P Ogbu, Anthony A Kossiakoff, Alex J Vecchio
Commun Biol. 2024 Jun 17;7(1):733. doi: 10.1038/s42003-024-06437-6.
PMID: 38886509 PMCID: PMC11183071 DOI: 10.1038/s42003-024-06437-6
Claudins are a 27-member family of ~25 kDa membrane proteins that integrate into tight junctions to form molecular barriers at …
Jun 20 2024
Tong Lan, Tomasz Slezak, Jinyue Pu, Julia Zinkus-Boltz, Sarbani Adhikari, Joel R. Pekow, Vibha Taneja, Joaquin Zuniga, Itzel A. Gómez-García, Nora Regino-Zamarripa, Mushtaq Ahmed, Shabaana A. Khader, David T. Rubin, Anthony A. Kossiakoff, and Bryan C. Dickinson
ACS Chem. Biol. June 6, 2024 © 2024 American Chemical Society
PMID: 38843544 …
Jun 20 2024
Lin Zhang, Hong-Chao Duan, Marcin Paduch, Jingyan Hu, Chi Zhang, Yajuan Mu, Houwen Lin, Chuan He, Anthony A. Kossiakoff, Guifang Jia, Liang Zhang
Zitierweise: Angew. Chem. Int. Ed. 2024, 63, e202313900
PMID: 38158383 DOI: 10.1002/ange.202313900
N1-methyladenosine (m1A) is a prevalent post-transcriptional RNA modification, and the distribution and dynamics …
Apr 03 2024
Hongtao Liu, Dariusz Zakrzewicz, Kamil Nosol, Rossitza N Irobalieva, Somnath Mukherjee, Rose Bang-Sørensen, Nora Goldmann, Sebastian Kunz, Lorenzo Rossi, Anthony A Kossiakoff, Stephan Urban, Dieter Glebe, Joachim Geyer, Kaspar P Locher
Nature Communications volume 15, Article number: 2476 (2024)
PMID: 38509088 PMCID: PMC10954734 DOI: 10.1038/s41467-024-46706-w
Cellular entry of …
Apr 03 2024
Szymon P. Kordon, Kristina Cechova, Sumit J. Bandekar, Katherine Leon, Przemysław Dutka, Gracie Siffer, Anthony A. Kossiakoff, Reza Vafabakhsh, and Demet Araç
bioRxiv 2024 Feb 26
PMID: 38464178 DOI: 10.1101/2024.02.25.581807
Adhesion G Protein-Coupled Receptors (aGPCRs) are key cell-adhesion molecules involved in numerous physiological functions. aGPCRs have large multi-domain …
Nov 21 2023
Heather A Bruce, Alexander U Singer, Ekaterina V Filippova, Levi L Blazer, Jarrett J Adams, Leonie Enderle, Moshe Ben-David, Elizabeth H Radley, Daniel Y L Mao, Victor Pau, Stephen Orlicky, Frank Sicheri, Igor Kourinov, Shane Atwell, Anthony A Kossiakoff, Sachdev S Sidhu
Protein Sci. 2023 Nov 9:e4824.
PMID: 37945533 DOI: …
Nov 06 2023
Rosemary J. Cater, Dibyanti Mukherjee, Eva Gil Iturbe, Satchal K. Erramilli, Ting Chen, Katie Koo, Nicolás Santander Grez, Andrew Reckers, Brian Kloss, Tomasz Gawda, Brendon C. Choy, Zhening Zheng, Oliver B. Clarke, Sook Wah Yee, Anthony A. Kossiakoff, Matthias Quick, Thomas Arnold, Filippo Mancia
bioRxiv. 2023 Oct 5:2023.10.05.561059.
PMID: 37873173 PMCID: PMC10592973 …